7 days of adequate antibiotic treatment

OTHER2 trials

Sponsors

Sunnybrook Health Sciences Centre

Conditions

AntimicrobialBacteremiaCritically IllIntensive CareMortalitySepsis

Unknown Phase

BALANCE on the Wards: A Pilot RCT

CompletedNCT02917551

Sunnybrook Health Sciences CentreBacteremia

Start: 2016-10-10End: 2020-01-30Updated: 2020-09-14

Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness

CompletedNCT03005145

Sunnybrook Health Sciences CentreAntimicrobial, Bacteremia, Critically Ill +3

Start: 2017-02-24End: 2023-08-03Updated: 2024-02-29

Related Papers

Accounting for non-adherence to assigned antibiotic treatment duration for bloodstream infection (BALANCE): a post-hoc analysis of a randomised clinical trial.

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Identifying heterogeneity of treatment effect for antibiotic duration in bloodstream infection: an exploratory post-hoc analysis of the BALANCE randomised clinical trial.

2025-04-102 citations

376. 7 versus 14 days of Antibiotic Treatment for Patients with Bloodstream Infections

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Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections

New England Journal of Medicine2024-11-2082 citations

Non-inferiority trial of a shorter (7 days) compared with a longer (14 days) duration of antimicrobial therapy for the treatment of bacteraemic urinary sepsis, measured by microbiological success after the completion of therapy: a substudy protocol for the Bacteraemia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE) multicentre randomised controlled trial

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Early oral stepdown antibiotic therapy versus continuing intravenous therapy for uncomplicated Gram-negative bacteraemia (the INVEST trial): study protocol for a multicentre, randomised controlled, open-label, phase III, non-inferiority trial.

2022-07-198 citations

Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE) randomised clinical trial: study protocol

BMJ Open2020-05-0126 citations

A pilot randomized controlled trial of 7 versus 14 days of antibiotic treatment for bloodstream infection on non-intensive care versus intensive care wards.

2020-01-158 citations