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6-Thioguanine

DRUG7 trials

Sponsors

Rutgers, The State University of New Jersey, Goethe University, Therapeutic Advances in Childhood Leukemia Consortium, M.D. Anderson Cancer Center, Memorial Sloan Kettering Cancer Center

Conditions

Acute Lymphoblastic LeukemiaAcute Lymphocytic LeukemiaAdult Acute Lymphocytic LeukemiaAnaplastic Glioma of BrainBrain CancerGlioblastoma MultiformeHodgkin's DiseaseLangerhans Cell Histiocytosis

Phase 1

ABT-751 With Chemotherapy for Relapsed Pediatric ALL
TerminatedNCT00439296
Therapeutic Advances in Childhood Leukemia ConsortiumAcute Lymphoblastic Leukemia, Recurrent Pediatric ALL, Refractory Pediatric ALL +1
Start: 2006-05-22End: 2009-09-23Updated: 2021-03-17
Study of 6-Thioguanine in Combination With 6-Mercaptopurine During Maintenance Therapy of Childhood Lymphoma
WithdrawnNCT02141100
Kjeld SchmiegelowNon-Hodgkin Lymphoma
Start: 2014-07-31End: 2016-10-31Updated: 2016-10-07

Phase 2

CINJALL: Treatment for Children With Acute Lymphocytic Leukemia
CompletedNCT00176462
Rutgers, The State University of New JerseyAcute Lymphocytic Leukemia
Start: 2001-02-28End: 2008-09-30Updated: 2014-06-09
6-TG, Capecitabine and Celecoxib Plus TMZ or CCNU for Anaplastic Glioma Patients
CompletedNCT00504660
M.D. Anderson Cancer CenterAnaplastic Glioma of Brain, Brain Cancer, Glioblastoma Multiforme
Start: 2003-09-30End: 2010-08-31Updated: 2012-01-11
Sequential Administration of Oral 6-Thioguanine (6-TG) After Methotrexate (MTX) in Patients With Relapsed Hodgkin's Disease (Phase II)
CompletedNCT00587873
Memorial Sloan Kettering Cancer CenterHodgkin's Disease
Start: 1994-03-31End: 2009-06-30Updated: 2009-06-12
Study of Sequential Administration of Oral 6-Thioguanine After Methotrexate in Patients With LCH
CompletedNCT00588536
Memorial Sloan Kettering Cancer CenterLangerhans Cell Histiocytosis
Start: 1995-01-31End: 2009-06-30Updated: 2015-05-04

Phase 4

German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (05/93)
CompletedNCT00199069
Goethe UniversityAdult Acute Lymphocytic Leukemia
Start: 1993-04-30End: 2001-05-31Target: 720Updated: 2023-03-17