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50 mg/ml

DRUG11 trials

Sponsors

CHRU De Nancy, Astrazeneca AB, Catharina Ziekenhuis Stichting, Medical University Of Gdansk, Moleculin Biotech Inc.

Conditions

Acute Myeloid LeukemiaCrohn's diseaseDiffuse large B-cell lymphoma) and aggressive B-cell lymphomas (HGBCLDiffuse large B-cell lymphomas (DLBCLHigh-grade B-cell lymphoma) originate from mature B-cells at various stages of terminal differentiationHistologically confirmed adenocarcinoma of the colon or rectum that is metastatic.Locally Advanced Unresectable Esophageal Squamous Cell CarcinomaLocally advanced rectal cancer

Phase 1

Phase 2

Phase 3

A Phase III, Randomized, Double-Blind, Placebo Controlled, Multi-Center, International Study of Durvalumab Given Concurrently With Definitive Chemoradiation Therapy in Patients With Locally Advanced, Unresectable Esophageal Squamous Cell Carcinoma (KUNLUN).
Active, not recruitingCTIS2023-506413-22-00
Astrazeneca ABLocally Advanced Unresectable Esophageal Squamous Cell Carcinoma
Start: 2021-03-31Target: 48Updated: 2026-01-09
Multicentre, open-label, randomized, controlled, parallel arms clinical trial of induction chemotherapy followed by chemoradiotherapy versus chemoradiotherapy alone as neoadjuvant treatment for locally recurrent rectal cancer (PelvEx II)
RecruitingCTIS2024-512526-28-00
Catharina Ziekenhuis StichtingLocally recurrent rectal cancer
Start: 2020-10-28Target: 364Updated: 2026-01-19
A Phase III, Randomized, Open-Label Clinical Study of Napabucasin in Combination with FOLFIRI and Best Supportive Care (BSC) Versus Napabucasin plus BSC in Adult Patients with Previously Treated Metastatic Colorectal Cancer (CRC)
Active, not recruitingCTIS2024-518204-50-00
1globe Health Institute LLCHistologically confirmed adenocarcinoma of the colon or rectum that is metastatic.
Start: 2022-04-25Target: 123Updated: 2025-12-10
A Randomized, Double-Blind, Placebo-Controlled Multicenter Study of Levosimendan Therapy in low ejection fraction Takotsubo Syndrome (LevoTako Trial)
CompletedCTIS2024-515060-32-00
Medical University Of GdanskTakotsubo syndrome
Start: 2024-11-22End: 2025-12-22Target: 190Updated: 2025-12-14
Evaluation of the efficacy of topical treatment with budesonide in children with Crohn's disease located in the esophagus and/or stomach and/or duodenum - BETHESDa
RecruitingCTIS2024-519269-23-00
Medical University Of WarsawCrohn's disease
Start: 2024-03-27Target: 138Updated: 2025-07-10
Impact of low dose epinephrine in the management of out-of-hospital cardiac arrest on neurological outcome: A multicenter randomized and double-blind trial (Low-EPI Study)
Not yet recruitingCTIS2023-505349-26-00
CHRU De NancyOut-of-hospital cardiac arrest.
Target: 4336Updated: 2025-10-08