50 mg/ml
Sponsors
CHRU De Nancy, Astrazeneca AB, Catharina Ziekenhuis Stichting, Medical University Of Gdansk, Moleculin Biotech Inc.
Conditions
Acute Myeloid LeukemiaCrohn's diseaseDiffuse large B-cell lymphoma) and aggressive B-cell lymphomas (HGBCLDiffuse large B-cell lymphomas (DLBCLHigh-grade B-cell lymphoma) originate from mature B-cells at various stages of terminal differentiationHistologically confirmed adenocarcinoma of the colon or rectum that is metastatic.Locally Advanced Unresectable Esophageal Squamous Cell CarcinomaLocally advanced rectal cancer
Phase 1
Phase 1/2 Study of Liposomal Annamycin in Combination with Cytarabine for the Treatment of Subjects with Acute Myeloid Leukemia (AML).
CompletedCTIS2024-516388-10-00
Start: 2022-09-23End: 2025-08-26Target: 24Updated: 2025-08-29
A Phase 1b/2 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Clinical Activity of GSK5764227 in combination with Standard of Care (SoC) or other agents in Participants with Advanced Solid Tumors
RecruitingCTIS2025-522274-37-00
Start: 2025-12-03Target: 15Updated: 2025-11-21
Phase 2
Neo-adjuvant FOLFOXIRI and chemoradiotherapy for high risk (“ugly”) locally advanced rectal cancer.
Active, not recruitingCTIS2023-509758-74-00
Start: 2021-07-21Target: 128Updated: 2024-03-25
Randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of nandrolone decanoate therapy and therapy with complex physiotherapy and diet in the treatment of sarcopenia
RecruitingCTIS2024-517178-48-00
Start: 2023-03-15Target: 168Updated: 2024-10-31
A phase II efficacy and safety study of cell-free circulating tumor DNA-guided commencement of second-line treatment in patients with DLBCL/HGBCL relapse
Not yet recruitingCTIS2024-518275-64-00
Target: 340Updated: 2025-11-24
Phase 3
A Phase III, Randomized, Double-Blind, Placebo Controlled, Multi-Center, International Study of Durvalumab Given Concurrently With Definitive Chemoradiation Therapy in Patients With Locally Advanced, Unresectable Esophageal Squamous Cell Carcinoma (KUNLUN).
Active, not recruitingCTIS2023-506413-22-00
Start: 2021-03-31Target: 48Updated: 2026-01-09
Multicentre, open-label, randomized, controlled, parallel arms clinical trial of induction chemotherapy followed by chemoradiotherapy versus chemoradiotherapy alone as neoadjuvant treatment for locally recurrent rectal cancer (PelvEx II)
RecruitingCTIS2024-512526-28-00
Start: 2020-10-28Target: 364Updated: 2026-01-19
A Phase III, Randomized, Open-Label Clinical Study of Napabucasin in Combination with FOLFIRI and Best Supportive Care (BSC) Versus Napabucasin plus BSC in Adult Patients with Previously Treated Metastatic Colorectal Cancer (CRC)
Active, not recruitingCTIS2024-518204-50-00
Start: 2022-04-25Target: 123Updated: 2025-12-10
A Randomized, Double-Blind, Placebo-Controlled Multicenter Study of Levosimendan Therapy in low ejection fraction Takotsubo Syndrome (LevoTako Trial)
CompletedCTIS2024-515060-32-00
Start: 2024-11-22End: 2025-12-22Target: 190Updated: 2025-12-14
Evaluation of the efficacy of topical treatment with budesonide in children with Crohn's disease located in the esophagus and/or stomach and/or duodenum - BETHESDa
RecruitingCTIS2024-519269-23-00
Start: 2024-03-27Target: 138Updated: 2025-07-10
Impact of low dose epinephrine in the management of out-of-hospital cardiac arrest on neurological outcome: A multicenter randomized and double-blind trial (Low-EPI Study)
Not yet recruitingCTIS2023-505349-26-00
Target: 4336Updated: 2025-10-08