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5 ml

DRUG15 trials

Sponsors

Centre Hospitalier Universitaire De Saint Etienne, Aalborg University Hospital, Institut Pasteur, Assistance Publique Hopitaux De Marseille, Hopital Fondation Adolphe De Rothschild

Conditions

Bacterial vaginosisBrain abscessCOVID-19 and fluCrohn’s DiseaseHigh risk preterm birth pregnancyHurley stage 2 active Hidradenitis SuppurativaHyperkalemiaIschemic stroke

Phase 2

Evaluation of the efficacy of intra venous dornase alfa (Pulmozyme®) on arterial recanalization in post-thrombectomy angiography in patients managed for ischemic stroke with thrombolysis and eligible for thrombectomy: a single-center phase II trial.
CompletedCTIS2024-515831-31-00
Fondation A De RothschildIschemic stroke
Start: 2022-08-19End: 2025-10-29Target: 44Updated: 2024-10-22
“NALPAC” A NON-COMPARATIVE RANDOMIZED PHASE 2 STUDY, EVALUATING THE EFFICACY OF 5-FU + NALIRI AND 5-FU + NALIRINOX FOR METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA (PDAC), PROGRESSIVE AFTER GEMCITABINE-ABRAXANE OR GEMCITABINE MONOTHERAPY.
RecruitingCTIS2024-516336-97-00
Groupe Belge D'Oncologie DigestiveMETASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Start: 2022-02-21Target: 134Updated: 2025-02-25
CONCOMITANT ADMINISTRATION OF LICENSED VACCINES AGAINST COVID-19 AND FLU WITH OR WITHOUT MF59 ADJUVANT: A MULTI-CENTRE, RANDOMIZED, SINGLE-BLIND CLINICAL TRIAL TO ASSESS IMMUNOGENICITY IN ADULTS AGED 65 AND OVER
CompletedCTIS2024-514798-23-00
Cr2o B.V.COVID-19 and flu
Start: 2024-10-02End: 2025-03-04Target: 120Updated: 2024-10-14
Efficacy of daily IV administration of dornase alfa for up to 14 days post subarachnoid haemorrhage on functional independence at 6 months: a multicentre open-label randomised controlled trial of the PROBE type Probe
Not yet recruitingCTIS2023-509627-40-01
Hopital Fondation Adolphe De Rothschildsubarachnoid hemorrhage
Target: 314Updated: 2025-09-24
Reduction of SystemiC Inflammation after ischemic stroke by intravenous DNase administration (ReSCInD)
Not yet recruitingCTIS2024-516701-22-00
Klinikum der Universitaet Muenchen AöRReduction of SystemiC Inflammation after ischemic stroke by intravenous DNase administration
Target: 36Updated: 2025-06-04

Phase 3

Best Antithrombotic Therapy in patients with acute Venous ThromboEmbolism while taking antiplatelets: the BAT-VTE
RecruitingCTIS2022-500974-33-00
Centre Hospitalier Universitaire De Saint Etienneacute venous thromboembolism event
Start: 2023-08-12Target: 1400Updated: 2025-04-25
A Multicentric Randomized Double-Blind Phase 3 Trial Evaluating the Efficacy of an Adapted Antibiotherapy in Hurley Stage 2 Active Hidradenitis Suppurativa Patients versus Tetracycline Derivative (ABCESS2)
RecruitingCTIS2023-505818-16-00
Institut PasteurHurley stage 2 active Hidradenitis Suppurativa
Start: 2025-05-22Target: 92Updated: 2026-01-15
TRAUMADORNASE A Prospective, Randomized Multicenter, Double Blind Clinical Trial Comparing Inhaled Dornase Alfa and Its Placebo to Reduce the Incidence of Moderate to Severe ARDS in Ventilated Trauma Patients in the Intensive Care Unit
RecruitingCTIS2024-512034-14-00
Les Hopitaux Universitaires De Strasbourgsevere trauma
Start: 2019-03-04Target: 500Updated: 2025-01-20
Comparison of azathioprine to methotrexate in combination therapy with adalimumab in Crohn’s Disease: an open-label randomized controlled trial
Not yet recruitingCTIS2024-514633-38-00
Centre Hospitalier Universitaire Amiens PicardieCrohn’s Disease
Target: 166Updated: 2025-10-15
BALLAD Belgium - A trial to evaluate the potential benefit of adjuvant chemotherapy for small bowel adenocarcinoma. The Belgian component of the Global Ballad pooled data analysis.
Not yet recruitingCTIS2024-518349-85-01
Groupe Belge D'Oncologie Digestivesmall bowel adenocarcinoma
Target: 30Updated: 2024-11-20
ANTIBIOBONTA - Assessment of the interest of a peri-operative antibiotic strategy applied to patients with asymptomatic bacteriuria undergoing intra-vesical botulinum toxin A injections
Not yet recruitingCTIS2024-515107-19-00
Centre Hospitalier Universitaire De LillePatients (male or female) ≥18 years old with Detrusor overactivity (DO) in multiple sclerosis (MS) or spinal cord injured (SCI).
Target: 526Updated: 2025-11-10
AUTOP 2 : Screen-and-treat strategy for vaginal flora abnormalities by molecular biology in pregnant women at high risk of preterm birth: A Multicentre, Randomized Study
Not yet recruitingCTIS2023-509421-41-03
Assistance Publique Hopitaux De MarseilleBacterial vaginosis, High risk preterm birth pregnancy, Vaginal flora abnormalities
Target: 1794Updated: 2026-04-01

Phase 4