5 mg/ml Pulver für ein Konzentrat zur Herstellung einer Infusionslösung
Sponsors
F. Hoffmann-La Roche AG, BeOne Medicines AG, Medical University Of Vienna, Dizal (Jiangsu) Pharmaceutical Co. Ltd.
Conditions
Chronic Lymphocytic Leukemia (CLL)Mantle Cell LymphomaMantle cell lymphomaRelapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Phase 2
Full title of the clinical trial: A Phase 3 Randomized, Open-Label, Multicenter Study Comparing Zanubrutinib (BGB-3111) plus Rituximab Versus Bendamustine plus Rituximab in Patients with Previously Untreated Mantle Cell Lymphoma Who Are Ineligible for Stem Cell Transplantation
RecruitingCTIS2023-509908-15-00
Start: 2020-01-20Target: 267Updated: 2025-10-17
Efficacy of Polatuzumab, Bendamustine and Rituximab in patients with relapsed/refractory mantle cell lymphoma- A single center phase II trial
CompletedCTIS2024-518704-41-00
Start: 2023-07-12End: 2025-06-17Target: 16Updated: 2024-12-10
Phase 3
A Prospective, Open-Label, Multicenter Randomized Phase III Study to Compare the Efficacy and Safety of a Combined Regimen of Venetoclax and Obinutuzumab Versus Fludarabine, Cyclophosphamide, and Rituximab (FCR)/ Bendamustine and Rituximab (BR) in FIT Patients with previously untreated Chronic Lymphocytic Leukemia (CLL) without DEL(17P) or TP53 Mutation
CompletedCTIS2023-504036-17-00
Start: 2020-05-07End: 2025-03-18Target: 121Updated: 2025-04-17
A Phase 3, Open-Label, Randomized, Multicenter Study to Evaluate Anti-tumor Efficacy of DZD8586 versus Investigator's Choice in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
RecruitingCTIS2025-522669-32-00
Start: 2025-12-18Target: 55Updated: 2025-11-13