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5 mg/ml

DRUG18 trials

Sponsors

Zealand University Hospital, Lysarc, Leiden University Medical Center, Aop Orphan Pharmaceuticals GmbH, Astrazeneca AB

Conditions

Acute law back painAdvanced/metastatic solid tumors that are MTAP deficient.Aortic Valve diseaseBacteriemia producida por P. aeruginosa.Breast cancerCardiogenic ShockDiffuse large B-cell lymphoma) and aggressive B-cell lymphomas (HGBCLDiffuse large B-cell lymphomas (DLBCL

Phase 1

Phase 2

Phase 3

A multicenter, double-blinded, randomized, placebo-controlled trial to compare the effectiveness of intratympanic injections methylPREDnisolone versus placebo in the treatment of vertigo attacks in MENière’s disease (PREDMEN trial).
RecruitingCTIS2023-503340-13-00
Leiden University Medical CenterMenière's disease
Start: 2023-10-05Target: 148Updated: 2024-11-18
MARSUN: Phase III, Multicenter, Open label, Randomized, Controlled Study Investigating Mosunetuzumab-Lenalidomide versus investigator choices in Patients with Relapsed or Refractory Marginal Zone Lymphoma
RecruitingCTIS2022-501810-77-00
LysarcRelapsed or Refractory Marginal Zone Lymphoma
Start: 2023-09-01Target: 260Updated: 2025-09-22
Randomized trial comparing efficacy and safety of initial triple therapy including parenteral treprostinil to initial double oral therapy in PAH group I patients – TripleTRE
RecruitingCTIS2023-504351-26-01
Aop Orphan Pharmaceuticals GmbHPulmonary arterial hypertension (group I)
Start: 2023-12-06Target: 123Updated: 2025-12-15
Anesthetic block of the erector muscles of the lumbar spine to relieve acute lumbar pain: pilot study
Not yet recruitingCTIS2024-511818-21-00
Sante AtlantiqueAcute law back pain
Target: 40Updated: 2025-05-28
Continuous Wound Infiltration versus placebo following elective minimally invasive colorectal surgery; a double-blinded, randomised, placebo-controlled, low-intervention trial (CIMICS trial)
RecruitingCTIS2024-512107-39-00
Catharina Ziekenhuis StichtingRecovery following elective minimally invasive colorectal surgery
Start: 2024-10-30Target: 192Updated: 2024-07-11
Effect of early use of levosimendan versus placebo on top of a conventional strategy of inotrope use on a combined morbidity-mortality endpoint in patients with cardiogenic shock. LevoHeartShock
RecruitingCTIS2024-513811-29-00
CHRU De NancyCardiogenic Shock
Start: 2023-07-03Target: 610Updated: 2025-07-30
LEONARD.LEvOsimendaN vs. Placebo Before Tricuspid VAlve Surgery in Patients with Right Ventricular Dysfunction (LEONARD)
Not yet recruitingCTIS2024-516167-86-00
Assistance Publique Hopitaux De ParisPatients referred for an isolated or a combined surgical correction of functional moderate to severe tricuspid regurgitation
Target: 230Updated: 2025-08-22
A Randomized, Double-Blind, Placebo-Controlled Multicenter Study of Levosimendan Therapy in low ejection fraction Takotsubo Syndrome (LevoTako Trial)
CompletedCTIS2024-515060-32-00
Medical University Of GdanskTakotsubo syndrome
Start: 2024-11-22End: 2025-12-22Target: 190Updated: 2025-12-14

Phase 4

The Intertransverse Process Block for Minor Breast Cancer Surgery – Single or Multiple Injection? A randomised, procedure related, blinded clinical trial.
WithdrawnCTIS2022-501312-34-00
Zealand University HospitalBreast cancer
Target: 30Updated: 2022-10-14
The Intertransverse Process Block - Single or Multiple Injection? A randomised, procedure related, blinded crossover trial in healthy volunteers
CompletedCTIS2022-501312-34-01
Zealand University HospitalThe ITP block is primarily used for pain amelioration after breast cancer surgery.
Start: 2023-02-26End: 2023-03-08Target: 12Updated: 2023-01-24
Efficacy of Intrathecal Morphine for Postoperative Analgesia with or without Suprainguinal Fascia Iliaca Block After Total Hip Arthroplasty: A Double-Blind Randomized Clinical Trial
RecruitingCTIS2024-511946-38-00
Centre hospitalier universitaire de LiegeTotal hip arthroplasty under spinal anesthesia
Start: 2024-06-12Target: 114Updated: 2024-05-08
Interpectoral-pectoserratus plane block for minimally invasive aortic valve replacement via right anterior minithoracotomy: A single centre, prospective, double-blind, randomized controlled superiority trial
RecruitingCTIS2023-509786-21-00
Az Maria Middelares GentAortic Valve disease
Start: 2024-09-01Target: 144Updated: 2024-08-12
Efficacy and safety of 7 versus 14 days of antibiotic treatment for bacteremia produced by Pseudomonas aeruginosa: a multicenter, randomized (SHORTEN-2) clinical trial with a DOOR/RADAR analysis.
Not yet recruitingCTIS2023-508441-41-00
Fundacion Publica Andaluza Para La Gestion De La Investigacion En Salud De SevillaBacteriemia producida por P. aeruginosa.
Target: 306Updated: 2025-07-25
Local Levobupivacaine for pain relief after Endoscopic Submucosal Dissection for esophageal lesions: a Randomized Controlled Trial
RecruitingCTIS2024-510912-66-00
Sint Antonius Ziekenhuis StichtingVisible esophageal lesions ((pre)cancerous)
Start: 2024-10-22Target: 88Updated: 2026-01-16

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