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DRUG3 trials

Sponsors

Turku University Central Hospital, Karolinska University Hospital, Oslo University Hospital HF

Conditions

Brain metastases from non-small-cell lung cancer (NSCLC) (Study B)Endometriosis in women with involuntary infertilityGlioblastoma - newly diagnosed and recurrent tumors (Study A)Non-metastatic HER2-positive Breast Cancer

Phase 2

A Randomized Trial of Trastuzumab Deruxtecan and Biology-Driven Selection of Neoadjuvant Treatment for HER2-positive Breast Cancer: ARIADNE
RecruitingCTIS2022-501504-95-00
Karolinska University HospitalNon-metastatic HER2-positive Breast Cancer
Start: 2023-06-23Target: 402Updated: 2025-08-18
Imaging Perfusion Restrictions from Extracellular Solid Stress - An open-label losartan study (ImPRESS)
Active, not recruitingCTIS2023-507575-22-00
Oslo University Hospital HFBrain metastases from non-small-cell lung cancer (NSCLC) (Study B), Glioblastoma - newly diagnosed and recurrent tumors (Study A)
Start: 2019-09-25Target: 153Updated: 2026-01-15

Phase 4

The effect of cabergoline in infertile women on peritoneal endometriosis related dysmenorrhea, chronic pelvic pain and fertility
WithdrawnCTIS2022-500792-31-00
Turku University Central HospitalEndometriosis in women with involuntary infertility
Target: 80Updated: 2022-12-22

Related Papers

Randomised trial of trastuzumab deruxtecan and biology-driven selection of neoadjuvant treatment for HER2-positive breast cancer: a study protocol of ARIADNE
BMJ Open2025-08-011 citations
Machine learning-based spatial characterization of tumor-immune microenvironment in the EORTC 10994/BIG 1-00 early breast cancer trial.
2025-03-073 citations