5 mg Hartkapseln
Sponsors
Exelixis Inc., Deciphera Pharmaceuticals Inc., F. Hoffmann-La Roche AG, Charite Universitaetsmedizin Berlin KöR, Universitaetsklinikum Schleswig-Holstein AöR
Conditions
Advanced Gastrointestinal Stromal TumorAdvanced or Metastatic Non-Clear Cell Renal Cell CarcinomaCaucasian paediatric kidney transplant recipientsICD 10: Z94.4 Liver transplant statusPatients with Advanced Gastrointestinal Stromal TumorsPrimary Membranous Nephropathy (pMN)Solid organ transplantation (Kidney)Solid organ transplantation (Liver)
Phase 1
A Phase I/IIa open label single ascending dose study to investigate the safety and tolerability of regulatory T cells as an adjunctive therapy in deceased-donor kidney recipients - ProTreg
RecruitingCTIS2024-514398-23-00
Start: 2024-06-10Target: 27Updated: 2025-09-10
A Phase I/IIa open label single ascending dose study to assess safety and tolerability of regulatory T cells to promote discontinuation of tacrolimus monotherapy in liver transplant recipients - LiveTreg
RecruitingCTIS2023-508261-32-00
Start: 2025-07-21Target: 27Updated: 2025-08-14
Phase 2
Phase 3
A Randomized Open-Label Phase 3 Study of XL092 + Nivolumab vs Sunitinib in Subjects with Advanced or Metastatic Non-Clear Cell Renal Cell Carcinoma
RecruitingCTIS2022-501703-27-00
Start: 2023-07-05Target: 196Updated: 2025-12-02
An International, Phase 3, Randomized, Multicenter, Open-label Study of Ripretinib vs Sunitinib in Patients with Advanced Gastrointestinal Stromal Tumor (GIST) with KIT Exon 11 and Co-occurring KIT Exons 17 and/or 18 Mutations Who Were Previously Treated with Imatinib (INSIGHT)
RecruitingCTIS2022-503058-37-00
Start: 2023-11-10Target: 30Updated: 2025-07-14
A Phase III, Randomized, Open-Label Active Comparator-Controlled Multicenter Study to Evaluate Efficacy and Safety of Obinutuzumab in Patients with Primary Membranous Nephropathy
Active, not recruitingCTIS2023-506525-11-00
Start: 2021-04-19Target: 52Updated: 2025-02-03
A Phase 3, Interventional, Randomized, Multicenter, Open-Label Study of DCC-2618 vs Sunitinib in Patients with Advanced Gastrointestinal Stromal Tumors after Treatment with Imatinib
Active, not recruitingCTIS2024-513277-52-00
Start: 2019-05-20Target: 144Updated: 2025-12-01