5 mg filmdragerade tabletter

DRUG4 trials

Sponsors

Karolinska University Hospital, Karolinska Institutet

Conditions

Climacteric symptomsEarly breast cancerEctopic pregnancyNon-metastatic HER2-positive Breast Cancer

Phase 2

A Randomized Trial of Trastuzumab Deruxtecan and Biology-Driven Selection of Neoadjuvant Treatment for HER2-positive Breast Cancer: ARIADNE

RecruitingCTIS2022-501504-95-00

Karolinska University HospitalNon-metastatic HER2-positive Breast Cancer

Start: 2023-06-23Target: 402Updated: 2025-08-18

Mifepristone and Letrozole versus methotrexate for treatment of Ectopic pregnancy - a randomized, controlled non-inferiority trial (MILE)

RecruitingCTIS2023-503935-16-00

Karolinska InstitutetEctopic pregnancy

Start: 2023-12-15Target: 316Updated: 2023-07-21

PREDIX Luminal B - Neoadjuvant response-guided treatment of estrogen receptor positive tumors with high proliferation or slow proliferation with metastatic nodes. Part of a platform of translational phase II trials based on molecular subtypes.

Active, not recruitingCTIS2024-519019-32-00

Karolinska University HospitalEarly breast cancer

Start: 2014-12-05Target: 180Updated: 2025-09-03

Phase 3

Safety of oral micronized progesterone versus norethisterone acetate in continuous combination with oral estrogen as menopausal hormone therapy – a double-blind randomized study- PROBES study (Progesterone Breast Endometrial Safety study)

Not yet recruitingCTIS2024-520435-33-00

Karolinska University HospitalClimacteric symptoms

Target: 520Updated: 2025-01-17

Related Papers

Randomised trial of trastuzumab deruxtecan and biology-driven selection of neoadjuvant treatment for HER2-positive breast cancer: a study protocol of ARIADNE

BMJ Open2025-08-011 citations

Machine learning-based spatial characterization of tumor-immune microenvironment in the EORTC 10994/BIG 1-00 early breast cancer trial.

2025-03-073 citations