4CMenB vaccine

BIOLOGICAL4 trials

Sponsors

St George's, University of London, Kirby Institute, Chinese University of Hong Kong, University of Oxford

Conditions

GonorrheaMeningococcal DiseaseNeisseria Gonorrheae InfectionPrematuritySexually Transmitted InfectionVaccinationgonorrhoea

Phase 2

Gonococcal vaccine study in key populations in Kenya

Active, not recruitingPACTR202009774604118

University of Oxfordgonorrhoea

Start: 2020-10-01Target: 50Updated: 2026-09-14

Phase 3

Efficacy Study of 4CMenB (Bexsero®) to Prevent Gonorrhoea Infection in Gay and Bisexual Men

Active, not recruitingNCT04415424

Kirby InstituteNeisseria Gonorrheae Infection

Start: 2021-07-08End: 2025-10-30Updated: 2025-03-24

Efficacy Trial on Meningococcal B Vaccine for Preventing Gonorrhea Infections

Active, not recruitingNCT05766904

Chinese University of Hong KongGonorrhea, Sexually Transmitted Infection

Start: 2023-05-04End: 2026-12-01Target: 150Updated: 2026-03-19

Phase 4

Babies Born Early Antibody Response to Men B Vaccination: BEAR Men B

CompletedNCT03125616

St George's, University of LondonMeningococcal Disease, Prematurity, Vaccination

Start: 2017-08-01End: 2020-08-28Updated: 2020-12-01

Related Papers

Meningococcal B Vaccine to Prevent <i>Neisseria gonorrhoeae</i> Infection.

2026-07-08

Efficacy of the 4CMenB vaccine against gonorrhoea among men who have sex with men in Hong Kong: a double-blind randomised placebo-controlled trial.

2026-06-26

Pertussis antibody responses in infants born to mothers vaccinated at different time points in pregnancy

Vaccine2025-07-15

An open-label, phase IV randomised controlled trial of two schedules of a four-component meningococcal B vaccine in UK preterm infants

Archives of Disease in Childhood2024-07-081 citations

Multicentre double-blind randomised placebo-controlled trial evaluating the efficacy of the meningococcal B vaccine, 4CMenB (Bexsero), against<i>Neisseria gonorrhoeae</i>infection in men who have sex with men: the GoGoVax study protocol

BMJ Open2024-04-018 citations

An Observational Study to Assess the Effectiveness of 4CMenB against Meningococcal Disease and Carriage and Gonorrhea in Adolescents in the Northern Territory, Australia—Study Protocol

Vaccines2022-02-1613 citations