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4-Aminopyridine

DRUG11 trials

Sponsors

University of California, Los Angeles, Columbia University, Coordinación de Investigación en Salud, Mexico, Massachusetts Eye and Ear Infirmary, University of Rochester

Conditions

Carpal Tunnel SyndromeChronicCompression NeuropathyCrush InjuryEpisodic Ataxia Type 2Migraine DisordersMultiple SclerosisNerve Injury

Phase 2

4-Aminopyridine in Episodic Ataxia Type 2
WithdrawnNCT01543750
University of California, Los AngelesEpisodic Ataxia Type 2
Updated: 2020-11-16
Short and Long Term Treatment With 4-AP in Ambulatory SMA Patients
CompletedNCT01645787
Columbia UniversitySpinal Muscular Atrophy
Start: 2012-06-01End: 2015-09-30Updated: 2024-09-03
Efficacy and Safety of 4-aminopyridine on Cognitive Performance and Motor Function of Patients With Multiple Sclerosis
CompletedNCT02280096
Coordinación de Investigación en Salud, MexicoMultiple Sclerosis
Start: 2014-10-31End: 2017-02-28Updated: 2019-09-12
4-Aminopyridine, Atenolol, or Placebo in Patients With Vestibular Migraine
WithdrawnNCT03578354
Massachusetts Eye and Ear InfirmaryMigraine Disorders, Vestibular Diseases, Vestibular Migraine
Start: 2019-01-31End: 2024-08-31Updated: 2024-07-01
4-aminopyridine Treatment for Nerve Injury From Radical Retro-Pubic Prostatectomy
WithdrawnNCT03658408
University of RochesterProstate Disease
Start: 2018-10-03End: 2018-10-30Updated: 2018-11-02
4-aminopyridine Treatment for Nerve Injury
RecruitingNCT03701581
John ElfarNerve Injury, Prostate Cancer
Start: 2021-06-05End: 2028-12-31Target: 70Updated: 2025-12-17
A Single Dose Pharmaco-Diagnostic for Peripheral Nerve Continuity After Trauma
TerminatedNCT04026568
Milton S. Hershey Medical CenterNerve Injury
Start: 2021-08-17End: 2022-07-18Updated: 2022-10-18
4-AP Peripheral Nerve Crossover Trial
RecruitingNCT06003166
University of ArizonaCrush Injury, Peripheral Nerve Injury
Start: 2025-04-21End: 2028-07-31Target: 68Updated: 2025-08-05
4AP for Carpal Tunnel Syndrome (CTS)
Not yet recruitingNCT06294821
John ElfarCarpal Tunnel Syndrome, Compression Neuropathy
Start: 2026-11-01End: 2028-07-01Target: 160Updated: 2026-01-26
4-aminopyridine for Skin Wound Healing
RecruitingNCT06333171
John ElfarWound Heal, Wound of Skin, Wounds +1
Start: 2025-09-30End: 2028-03-31Target: 150Updated: 2025-09-03

Phase 3

High Doses of 4-aminopyridine in Clinically Complete Chronic Spinal Cord Injury Patients.
NCT03899584
Coordinación de Investigación en Salud, MexicoChronic, Spinal Cord Injuries
Start: 2019-07-17End: 2023-12-31Updated: 2021-02-21

Related Papers

4-Aminopyridine treatment for nerve injury resulting from radical retro-pubic prostatectomy: a single-center double-blind, randomized, placebo-controlled study
Trials2024-05-211 citations
Effects of 4-aminopyridine on attention and executive functions of patients with multiple sclerosis: Randomized, double-blind, placebo-controlled clinical trial. Preliminary report.
2018-12-1910 citations