21.15.GPC3-CAR T cells
Sponsors
Baylor College of Medicine
Conditions
Atypical Teratoid Rhabdoid TumorCentral Nervous System Rhabdoid TumorEmbryonal Sarcoma of LiverHepatoblastomaHepatocellular CarcinomaLiposarcomaMalignant Rhabdoid TumorRhabdomyosarcoma
Phase 1
Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells
RecruitingNCT06198296
Start: 2025-06-10End: 2043-02-01Target: 21Updated: 2025-11-03
GPC3 CAR T Cells With IL-15 and IL-21 for Recurrent ATRT and CNS Rhabdoid Tumors (RADIANT)
Not yet recruitingNCT07513194
Start: 2026-09-01End: 2044-10-31Target: 21Updated: 2026-04-07