20% D-glucose (aq)

DRUG3 trials

Sponsors

Columbia University

Conditions

HyperinsulinemiaInsulin ResistanceMetabolic Dysfunction Associated Steatotic Liver DiseaseNon-Alcoholic Fatty Liver DiseaseObesityOverweight and ObesityPrediabetic State

Phase 1

Pancreatic Clamp in NAFLD

CompletedNCT05724134

Columbia UniversityHyperinsulinemia, Insulin Resistance, Non-Alcoholic Fatty Liver Disease +2

Start: 2023-08-29End: 2025-09-24Updated: 2026-01-12

Dexamethasone/Pancreatic Clamp P&F

WithdrawnNCT06126354

Columbia UniversityInsulin Resistance, Non-Alcoholic Fatty Liver Disease, Overweight and Obesity +1

Start: 2024-07-01End: 2026-03-31Updated: 2024-07-10

Human Models of Selective Insulin Resistance: Pancreatic Clamp

Not yet recruitingNCT06558422

Columbia UniversityHyperinsulinemia, Insulin Resistance, Metabolic Dysfunction Associated Steatotic Liver Disease +3

Start: 2027-01-01End: 2029-02-28Target: 36Updated: 2026-02-06