2-HOBA

DIETARY_SUPPLEMENT6 trials

Sponsors

Metabolic Technologies Inc., Vanderbilt University Medical Center

Conditions

Healthy AdultsHealthy VolunteersOlder AdultsPulmonary Arterial HypertensionRheumatoid Arthritis

Phase 2

2-HOBA Phase 2 Clinical Trial in Rheumatoid Arthritis

CompletedNCT05274243

Vanderbilt University Medical CenterRheumatoid Arthritis

Start: 2022-08-09End: 2025-05-28Updated: 2026-04-08

Clinical Trial of 2-HOBA in Pulmonary Arterial Hypertension

Not yet recruitingNCT06176118

Vanderbilt University Medical CenterPulmonary Arterial Hypertension

Start: 2026-09-01End: 2027-12-01Target: 12Updated: 2026-06-17

Unknown Phase

2-HOBA: Initial Evaluation in Humans

CompletedNCT03176940

Metabolic Technologies Inc.Healthy Volunteers

Start: 2017-08-02End: 2018-04-30Updated: 2018-06-04

Brain Penetrance of 2-HOBA in Humans

CompletedNCT03554096

Metabolic Technologies Inc.Healthy Adults

Start: 2018-05-23End: 2019-02-08Updated: 2019-02-20

2-HOBA: Multiple Dosing Study in Healthy Humans

CompletedNCT03555682

Metabolic Technologies Inc.Healthy Volunteers

Start: 2018-05-23End: 2019-05-10Updated: 2019-08-13

2-HOBA: Multiple Dosing Study in Older Adults

CompletedNCT03556319

Metabolic Technologies Inc.Older Adults

Start: 2018-05-23End: 2021-07-31Updated: 2021-12-14

Related Papers

Safety, tolerability, and pharmacokinetics of repeated oral doses of 2-hydroxybenzylamine acetate in healthy volunteers: a double-blind, randomized, placebo-controlled clinical trial

BMC Pharmacology and Toxicology2020-01-0626 citations

First-in-human study assessing safety, tolerability, and pharmacokinetics of 2-hydroxybenzylamine acetate, a selective dicarbonyl electrophile scavenger, in healthy volunteers

BMC Pharmacology and Toxicology2019-01-0536 citations