18F-PF-06445974

DRUG3 trials

Sponsors

National Institute of Mental Health (NIMH)

Conditions

Alcohol Use DisorderDepression

Phase 1

[18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET

RecruitingNCT05703685

National Institute of Mental Health (NIMH)Depression

Start: 2023-06-22End: 2029-04-11Target: 108Updated: 2026-08-17

PET Imaging of Phosphodiesterase-4B (PDE4B) in Alcohol Use Disorder

RecruitingNCT06795581

National Institute of Mental Health (NIMH)Alcohol Use Disorder

Start: 2025-03-20End: 2029-01-31Target: 30Updated: 2026-09-18

Acute Effects of Alcohol on PET Imaging of Phosphodiesterase-4B (PDE4B)

RecruitingNCT07027839

National Institute of Mental Health (NIMH)Alcohol Use Disorder

Start: 2025-12-11End: 2029-02-22Target: 30Updated: 2026-08-17