18F-MFBG

DRUG7 trials

Sponsors

Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC), Peking Union Medical College Hospital, First Affiliated Hospital of Zhejiang University

Conditions

Lewy Body Dementia (LBD)NeuroblastomaNeuroendocrine TumorParagangliomaParkinson Disease (PD)Pheochromocytoma

Early Phase 1

18F-MFBG PET/CT in the Evaluation of Neural Crest Tumor

RecruitingNCT05069220

Peking Union Medical College HospitalNeuroblastoma, Neuroendocrine Tumor, Paraganglioma +1

Start: 2021-09-01End: 2026-12-31Target: 150Updated: 2024-03-01

Phase 2

18F-mFBG Expression in Neural Crest Tumors and Organs Innervated by the Sympathetic Nervous System

WithdrawnNCT06233903

Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC)Neuroblastoma, Paraganglioma, Pheochromocytoma

Start: 2025-01-31End: 2025-12-31Updated: 2025-01-21

18F-mFBG Cardiac Uptake With Lewy Body Dementia

RecruitingNCT07176286

Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC)Lewy Body Dementia (LBD), Parkinson Disease (PD)

Start: 2026-04-30End: 2026-12-30Target: 20Updated: 2026-07-01

Phase 3

Open-Label Study of 18F-mFBG for Imaging Neuroblastoma

CompletedNCT04724369

Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC)Neuroblastoma

Start: 2021-11-18End: 2026-08-30Updated: 2026-09-29

Unknown Phase

18F-mFBG PET Imaging in the Evaluation of Pheochromocytoma

RecruitingNCT06813742

First Affiliated Hospital of Zhejiang UniversityPheochromocytoma

Start: 2023-05-01End: 2026-12-31Target: 80Updated: 2025-08-07

18F-mFBG PET Imaging in the Evaluation of Neuroblastoma

RecruitingNCT06852807

First Affiliated Hospital of Zhejiang UniversityNeuroblastoma

Start: 2025-02-04End: 2029-12-31Target: 200Updated: 2025-08-08

A Prospective Image Reevaluation Study to Assess the Efficacy of 18F-mFBG PET Imaging in Subjects With Neuroblastoma

CompletedNCT07833631

Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC)Neuroblastoma

Start: 2026-06-01End: 2026-08-31Updated: 2026-09-22

Related Papers

[<sup>18</sup>F]MFBG PET/CT is an effective and preferable imaging modality for neuroblastoma in a prospective comparison with SSTR PET.

2025-07-28

[<sup>18</sup>F]MFBG PET/CT outperforming [<sup>123</sup>I]MIBG SPECT/CT in the evaluation of neuroblastoma.

2023-05-0928 citations