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18F-fluciclovine

DRUG10 trials

Sponsors

Norwegian University of Science and Technology, Timothy J. Daskivich, Case Comprehensive Cancer Center, Brigham and Women's Hospital, James Mountz

Conditions

Advanced Prostate CancerBladder CancerBrain CancerBrain MetastasesCentral Nervous System NeoplasmsGliomaGlioma IntracranialGlioma, Malignant

Early Phase 1

18F-Fluciclovine PET to Distinguish Tumor Progression From Radiation Necrosis
CompletedNCT03930173
Case Comprehensive Cancer CenterSecondary Malignant Neoplasm of Brain and Cerebral Meninges
Start: 2019-07-02End: 2021-03-01Updated: 2021-05-05
18Fluorine-Fluciclovine PET/CT for Staging Muscle Invasive Bladder Cancer Preceding Radical Cystectomy
Active, not recruitingNCT04018053
Brigham and Women's HospitalBladder Cancer, Urothelial Carcinoma
Start: 2020-02-26End: 2026-07-01Updated: 2026-01-27
Evaluation of 18F-fluciclovine (FACBC) PET/MR Uptake in Participants With Glioma
CompletedNCT04114370
James MountzGlioma
Start: 2019-10-22End: 2021-09-30Updated: 2022-12-06
18F-Fluciclovine PET/CT in the Assessment of Pancreatic Transplants
CompletedNCT04852523
University of UtahPancreatic Transplant Post-Transplant Dysfunction Rejection, Pancreatitis, Graft
Start: 2021-09-16End: 2022-10-06Updated: 2024-09-03
Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG
RecruitingNCT05555550
Children's Hospital of PhiladelphiaGlioma, Glioma Intracranial, Glioma, Malignant +2
Start: 2025-12-29End: 2027-09-30Target: 30Updated: 2025-12-04

Phase 1

Pilot Study for Detection of PSMA-Low CRPC-NE Tumors With Fluciclovine PET/CT
RecruitingNCT06062745
Brigham and Women's HospitalAdvanced Prostate Cancer, Metastatic Prostate Cancer, Metastatic Prostate Neuroendocrine Carcinoma
Start: 2024-02-01End: 2028-09-01Target: 30Updated: 2025-11-05

Phase 2

High Resolution PET-MRI Before Prostate Cancer HIFU
CompletedNCT03263780
Timothy J. DaskivichProstate Cancer
Start: 2017-12-07End: 2020-01-08Updated: 2021-02-21
Characterization of 18F-Fluciclovine PET Amino Acid Radiotracer in Resected Brain Metastasis
RecruitingNCT05554302
Baptist Health South FloridaBrain Cancer, Brain Metastases
Start: 2023-01-10End: 2030-01-31Target: 20Updated: 2025-12-01

Unknown Phase

Diagnostic Assessment of 18F-fluciclovine and 18F-FDG -PET/MRI of Primary Central Nervous System Lymphoma
CompletedNCT03188354
Norwegian University of Science and TechnologyCentral Nervous System Neoplasms, Lymphoma, Non-Hodgkin
Start: 2017-11-01End: 2023-12-31Updated: 2024-01-05
A Prospective Pilot Study for the Evaluation of 18F- Fluciclovine PET/MRI in Radio-recurrent Prostate Cancer (RRPC-PET/MRI Study)
WithdrawnNCT05035732
M.D. Anderson Cancer CenterProstate Cancer, Prostate Nodule
Start: 2021-03-25End: 2024-01-17Updated: 2024-01-18

Related Papers

A pilot study of [<sup>18</sup>F]F-fluciclovine positron emission tomography/computed tomography for staging muscle invasive bladder cancer preceding radical cystectomy.
2025-04-21
<sup>18</sup>F-FACBC and <sup>18</sup>F-FDG PET/MRI in the evaluation of 3 patients with primary central nervous system lymphoma: a pilot study.
2024-01-312 citations