11C-PBR28

DRUG4 trials

Sponsors

Columbia University, Patrick Lao, Washington University School of Medicine, Massachusetts General Hospital

Conditions

Abdominal Aortic Aneurysm (AAA)Alzheimer's DiseaseDementia With Lewy BodiesDiffuse Lewy Body DiseaseMultiple SclerosisParkinson's Disease Dementia

Phase 2

Imaging Inflammation in Patients With Parkinson's Disease Dementia or Dementia With Lewy Bodies

CompletedNCT02702102

Columbia UniversityDementia With Lewy Bodies, Diffuse Lewy Body Disease, Parkinson's Disease Dementia

Start: 2015-12-31End: 2019-09-04Updated: 2025-03-18

Imaging Inflammation in Alzheimer's Disease

CompletedNCT02831283

Patrick LaoAlzheimer's Disease

Start: 2016-06-30End: 2022-12-31Updated: 2025-03-05

Phase 4

Predictors of AAA Expansion and/or Rupture

TerminatedNCT03231397

Washington University School of MedicineAbdominal Aortic Aneurysm (AAA)

Start: 2017-08-01End: 2020-04-30Updated: 2021-07-09

Effect of Ocrelizumab on Neuroinflammation in Multiple Sclerosis as Measured by 11C-PBR28 MR-PET Imaging of Microglia Activation

CompletedNCT04230174

Massachusetts General HospitalMultiple Sclerosis

Start: 2020-12-29End: 2025-04-30Updated: 2025-12-30

Related Papers

Olfactory Impairment Is Related to Tau Pathology and Neuroinflammation in Alzheimer’s Disease

Journal of Alzheimer s Disease2021-02-2051 citations