11C-ER176

DRUG6 trials

Sponsors

Columbia University, National Institute of Mental Health (NIMH), Jose Gutierrez, MD, MPH, Patrick Lao, The Methodist Hospital Research Institute

Conditions

Alzheimer DiseaseDementia

Phase 1

Imaging Inflammation in Alzheimer's Disease With 11C-ER176

CompletedNCT03744312

Columbia UniversityAlzheimer Disease

Start: 2018-09-10End: 2022-07-20Updated: 2025-04-17

PET Imaging of Neuroinflammation in Neurodegenerative Diseases Via a Novel Translocator Protein (TSPO) Radioligand

TerminatedNCT03958630

National Institute of Mental Health (NIMH)Dementia

Start: 2019-07-03End: 2023-12-04Updated: 2024-05-01

Phase 2

Longitudinal Imaging of Microglial Activation in Different Clinical Variants of Alzheimer's Disease

RecruitingNCT04576793

Patrick LaoAlzheimer Disease

Start: 2020-11-17End: 2026-05-31Target: 100Updated: 2025-07-03

Discovery and Validation of Genetic Variants Affecting Microglial Activation in Alzheimer's Disease

RecruitingNCT04840979

Columbia UniversityAlzheimer Disease

Start: 2021-05-11End: 2026-12-31Target: 250Updated: 2025-04-24

Systemic and Central Inflammation in AD

RecruitingNCT06384378

The Methodist Hospital Research InstituteAlzheimer Disease

Start: 2023-03-17End: 2025-12-30Target: 40Updated: 2024-04-25

Unknown Phase

Accelerated Non-Atherosclerotic Brain Arterial Aging Relationship to Alzheimer's Disease

CompletedNCT04510168

Jose Gutierrez, MD, MPHAlzheimer Disease, Dementia

Start: 2020-09-18End: 2024-04-17Updated: 2024-07-16