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0.9% Sodium Chloride Solution for Injection

DRUG8 trials

Sponsors

Janssen - Cilag International, Bristol-Myers Squibb Services Unlimited Company, Janssen Cilag International, Bristol Myers Squibb International Corporation, Sirius Therapeutics Inc.

Conditions

Active Idiopathic Inflammatory Myopathies (IIM)Advanced solid tumorsChronic Inflammatory Demyelinating PolyneuropathyFetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)Hemolytic Disease of the Fetus and Newborn (HDFN)Resectable Stage II-IIIB Non-small cell lung cancerRheumatoid Arthritisvenous thromboembolism

Phase 1

Phase 2

A Phase 2a Multicenter, Randomized, Double Blind, Parallel-group, Proof of Concept Study Evaluating the Efficacy and Safety of Nipocalimab and Certolizumab Combination Therapy in Subjects with Active Rheumatoid Arthritis despite Prior Treatment with Advanced Therapies (bDMARD or tsDMARD)
CompletedCTIS2023-504045-31-00
Janssen - Cilag InternationalRheumatoid Arthritis
Start: 2024-02-08End: 2024-10-29Target: 55Updated: 2024-10-16
A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Efficacy and Safety of Nipocalimab in Participants with Active Idiopathic Inflammatory Myopathies
Active, not recruitingCTIS2023-505314-20-00
Janssen - Cilag InternationalActive Idiopathic Inflammatory Myopathies (IIM)
Start: 2023-01-20Target: 62Updated: 2025-10-22
Phase 2/3, Multistage, Multicenter, Randomized, Double-Blind, Placebo-Controlled Parallel Group Withdrawal Study to Evaluate the Efficacy and Safety of Nipocalimab Administered to Adults with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
RecruitingCTIS2023-508425-28-00
Janssen Cilag InternationalChronic Inflammatory Demyelinating Polyneuropathy
Start: 2022-10-24Target: 42Updated: 2026-01-07
A Multicenter, Randomized, Open-Label, Blinded Endpoint Evaluation, Active-Controlled Study to Compare the Efficacy and Safety of SRSD107 and Enoxaparin in Adult Subjects Undergoing Elective Primary Unilateral Total Knee Arthroplasty.
RecruitingCTIS2024-519688-16-00
Sirius Therapeutics Inc.venous thromboembolism
Start: 2025-08-07Target: 450Updated: 2025-10-28

Phase 3