0.9% sodium chloride for injection

DRUG3 trials

Sponsors

Glaxosmithkline Research & Development Limited, Peking University First Hospital

Conditions

C.Surgical Procedure; CardiacCardiac SurgeryDeliriumDexmedetomidineLong-term OutcomeLung CancerMortalityNon-Small Cell

Phase 3

A randomized, multicenter, double-blind, Phase 3 study to investigate the safety and efficacy of belrestotug in combination with dostarlimab compared with placebo in combination with pembrolizumab in participants with previously untreated, locally advanced, unresectable or metastatic PD-L1 selected non small cell lung cancer (GALAXIES LUNG 301)

Active, not recruitingCTIS2023-504753-12-00

Glaxosmithkline Research & Development LimitedLung Cancer, Non-Small Cell

Start: 2024-10-01Target: 328Updated: 2025-10-31

Phase 4

Dexmedetomidine and Delirium in Patients After Cardiac Surgery

CompletedNCT02267538

Peking University First HospitalC.Surgical Procedure; Cardiac, Delirium, Postoperative Complications

Start: 2014-11-30End: 2015-11-30Updated: 2018-03-05

Unknown Phase

Dexmedetomidine and Long-term Outcomes in Elderly Patients After Cardiac Surgery

CompletedNCT03289325

Peking University First HospitalCardiac Surgery, Dexmedetomidine, Long-term Outcome +2

Start: 2021-10-21End: 2022-05-03Updated: 2024-10-01

Related Papers

Impact of perioperative dexmedetomidine on long-term outcomes in older patients following cardiac surgery: follow-up of a randomized trial

BMC Anesthesiology2025-03-172 citations

Impact of dexmedetomidine on the incidence of delirium in elderly patients after cardiac surgery: A randomized controlled trial

PLoS ONE2017-02-09158 citations