(over 1week for washout) -&gt

3 trials

Sponsors

P-One Clinic,Keikokai Medical Corp.

Conditions

Healthy volunteers (Japanese male)

Unknown Phase

Drug-drug interaction study with the cocktail administration of semi-pharmacological dose of multiple drugs to determine the quantitative contribution of OATPs and CYP3A4 to the clearance of the substrate drugs of both OATPs and CYP3A4.

Active, not recruitingJPRN-UMIN000024790

P-One Clinic,Keikokai Medical Corp.Healthy volunteers (Japanese male)

Start: 2014-08-01Target: 8Updated: 2026-06-29

Study for drug-drug interactions involving hepatic OATPs using its endogenous substrates

Active, not recruitingJPRN-UMIN000028684

P-One Clinic,Keikokai Medical Corp.Healthy volunteers (Japanese male)

Start: 2016-04-01Target: 8Updated: 2026-06-29

OPEN-LABEL, RANDOMIZED, CROSSOVER STUDY TO ASSESS THE DOSE-DEPENDENT EFFECT OF RIFAMPICIN ON THE PHARMACOKINETICS OF ENDOGENOUS BIOMARKERS AND PROBE DRUGS FOR ASSESSMENT OF DRUG-DRUG INTERACTIONS MEDIATED BY OATP1B

Active, not recruitingJPRN-UMIN000033695

P-One Clinic,Keikokai Medical Corp.Healthy volunteers (Japanese male)

Start: 2018-02-01Target: 8Updated: 2026-06-29