[18F]FAPI-74 PET/CT

DRUG5 trials

Sponsors

SOFIE, Leiden University Medical Center, Martin Huellner

Conditions

Breast CancerCholangiocarcinomaColorectal CancerEndometriosis (Diagnosis)Esophageal CancerGastric CancerGastric Cancer (GC)Gastroesophageal Junction

Phase 1

FAPI PET Imaging - An Exploratory Study

Not yet recruitingNCT07705074

Martin HuellnerBreast Cancer, Endometriosis (Diagnosis), Gastric Cancer (GC) +14

Start: 2026-08-01End: 2029-09-01Target: 770Updated: 2026-07-15

Phase 2

Study of [18F]FAPI-74 PET in Patients With Gastrointestinal Cancers

CompletedNCT05641896

SOFIECholangiocarcinoma, Colorectal Cancer, Gastric Cancer +3

Start: 2023-04-28End: 2025-06-30Updated: 2026-01-22

[18F]F-FAPI PET/CT and Laparoscopy in Staging Advanced Gastric Cancer

RecruitingNCT07018661

Leiden University Medical CenterGastric Cancer, Locally Advanced Gastric Adenocarcinoma, PET-CT +1

Start: 2025-07-03End: 2029-01-31Target: 250Updated: 2025-08-27

Phase 3

Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Pancreatic Ductal Adenocarcinoma (PDAC)

RecruitingNCT07217717

SOFIEPancreatic Ductal Adenocarcinoma (PDAC)

Start: 2025-12-11End: 2027-12-31Target: 200Updated: 2026-09-17

Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Gastric or Esophageal Cancer.

RecruitingNCT07217704

SOFIEEsophageal Cancer, Gastric Cancer (GC), Gastroesophageal Junction

Start: 2025-11-14End: 2027-08-30Target: 200Updated: 2026-09-17

Related Papers

Use of PPV of [ <sup>18</sup> F]FAPI-74 PET to identify FAP expression in gastrointestinal cancers: Results from a prospective multicenter phase 2 study.

Journal of Clinical Oncology2026-01-10

Current status of FAP therapy in solid tumors.

2025-12-26

[<sup>18</sup>F]F-FAPI PET/CT and LAparoscopy in STagIng advanced gastric Cancer: a multicenter prospective study (PLASTIC-3 study).

2025-11-27