[18F]AlF-FAPI-74 PET/CT

DIAGNOSTIC_TEST2 trials

Sponsors

KU Leuven, Universitaire Ziekenhuizen KU Leuven

Conditions

Axial Spondylarthritis (axSpA)FAPFever of Unknown OriginGastric CancerIgG4 Related DiseaseInflammation of Unknown OriginOesophageal CancerOncologic Disorders

Phase 2

Multicenter Validation Trial of [18F]AlF-FAPI-74 for PET Imaging of Cancer-associated Fibroblasts Through Fibroblast Activation Protein Inhibitors (FAPI) in Different Tumor Types

RecruitingNCT06782412

KU LeuvenFAP, Gastric Cancer, Oesophageal Cancer +3

Start: 2025-02-06End: 2027-12-31Target: 109Updated: 2025-02-07

The Investigators Will Evaluate the Diagnostic Performance of [18F]-AlF-FAPI-74 PET/CT in Inflammatory Disorders and Compare it With the Current Gold Standard for Inflammation, FDG PET/CT, in Three Patient Cohort: Patients Presenting With Fever of Unknown Origin, IgG4-RD and AxSpA.

RecruitingNCT07535554

Universitaire Ziekenhuizen KU LeuvenAxial Spondylarthritis (axSpA), Fever of Unknown Origin, IgG4 Related Disease +1

Start: 2025-09-17End: 2030-03-31Target: 140Updated: 2026-04-17