[11C]NNC-112

DRUG3 trials

Sponsors

National Institute of Mental Health (NIMH), National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Conditions

Alcohol Use Disorder (AUD)HealthyNormal PhysiologyOpioid Use Disorders

Early Phase 1

Brain Dopaminergic Signaling in Opioid Use Disorders

CompletedNCT03190954

National Institute on Alcohol Abuse and Alcoholism (NIAAA)Normal Physiology, Opioid Use Disorders

Start: 2017-08-17End: 2025-10-27Updated: 2026-09-08

Phase 1

Positron Emission Tomography Imaging of Dopamine Receptors Using the Tracer [11C]NNC-112

CompletedNCT00088517

National Institute of Mental Health (NIMH)Healthy

Start: 2004-07-31End: 2006-03-31Target: 10Updated: 2008-03-04

Tirzepatide s Dopaminergic Effects in Alcohol Use Disorders (AUD)

RecruitingNCT07559500

National Institute on Alcohol Abuse and Alcoholism (NIAAA)Alcohol Use Disorder (AUD)

Start: 2026-05-20End: 2031-12-31Target: 176Updated: 2026-07-28

Related Papers

Dopamine D1 and D2 receptors are distinctly associated with rest-activity rhythms and drug reward

Journal of Clinical Investigation2021-07-1535 citations